9-1-1 Cell-Cycle Checkpoint Complex as Cancer Treatment Target

Target Name: 9-1-1 cell-cycle checkpoint response complex

NCBI ID: P25399

Other Name(s): Toroidal damage checkpoint complex | RAD9-RAD1-HUS1 complex

9-1-1 Cell-Cycle Checkpoint Complex as Cancer Treatment Target

The 9-1-1 cell-cycle checkpoint response complex, also known as the Toroidal damage checkpoint complex, is a protein complex that plays a critical role in regulating cell division and preventing tumorigenesis. It is composed of several key components, including Checkpoint protein 1 (CP-1), Checkpoint protein 2 (CP-2), and Checkpoint protein 3 (CP-3), which work together to ensure that cells divide properly and do not undergo apoptosis.

The 9-1-1 cell-cycle checkpoint response complex was identified as a potential drug target by researchers because it is highly expressed in various tissues, including the brain, and it is involved in cell division and survival. Studies have also shown that inhibiting the activity of the 9-1-1 cell-cycle checkpoint response complex has anti-tumor effects, suggesting that it may be a promising target for cancer treatment.

The 9-1-1 cell-cycle checkpoint response complex is a complex that is essential for cell survival and proper cell division. It plays a crucial role in regulating the cell cycle, which is the process by which cells grow, divide, and maintain their genetic material. The 9-1-1 cell-cycle checkpoint response complex ensures that cells divide properly and do not undergo apoptosis, which is a process that causes cells to die.

The 9-1-1 cell-cycle checkpoint response complex is composed of several key components, including Checkpoint protein 1 (CP-1), Checkpoint protein 2 (CP-2), and Checkpoint protein 3 (CP-3). These proteins work together to ensure that cells divide properly and do not undergo apoptosis. Checkpoint protein 1 and Checkpoint protein 2 are involved in the regulation of the G1/S transition, which is the stage of the cell cycle where cells prepare for cell division. Checkpoint protein 3 is involved in the regulation of the G2/M transition, which is the stage of the cell cycle where cells prepare for cell growth.

The 9-1-1 cell-cycle checkpoint response complex is highly expressed in various tissues, including the brain, heart, and gastrointestinal tract. It is also involved in the development and progression of various diseases, including cancer. Studies have shown that inhibiting the activity of the 9-1-1 cell-cycle checkpoint response complex has anti-tumor effects, suggesting that it may be a promising target for cancer treatment.

In addition to its role in cell division and survival, the 9-1-1 cell-cycle checkpoint response complex is also involved in the regulation of cellular processes that are important for brain function. The 9-1-1 cell-cycle checkpoint response complex has been shown to be involved in the regulation of neurogenesis, which is the process by which new neurons are produced in the brain. It is also involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time.

Overall, the 9-1-1 cell-cycle checkpoint response complex is a protein complex that is essential for cell survival and proper cell division. It plays a crucial role in regulating the cell cycle and ensuring that cells divide properly and do not undergo apoptosis. The 9-1-1 cell-cycle checkpoint response complex is highly expressed in various tissues and is involved in the development and progression of various diseases, including cancer. inhibiting its activity may be a promising target for cancer treatment.

Protein Name: 9-1-1 Cell-cycle Checkpoint Response Complex

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